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Elsaid, E., Tarik, Z., Eman, M., Mostafa, E., Ahmed, A., Mohamed, A., Hoda, E. (2020). Management of chronic hepatitis B in special populations. Medical Journal of Viral Hepatitis, 4.2(2), 63-68. doi: 10.21608/mjvh.2020.80654
Elbadrawy Elsaid; Zaher Tarik; Mousa Eman; Elshenaway Mostafa; Alhawarey Ahmed; Abdel-Aziz Mohamed; Elgamal Hoda. "Management of chronic hepatitis B in special populations". Medical Journal of Viral Hepatitis, 4.2, 2, 2020, 63-68. doi: 10.21608/mjvh.2020.80654
Elsaid, E., Tarik, Z., Eman, M., Mostafa, E., Ahmed, A., Mohamed, A., Hoda, E. (2020). 'Management of chronic hepatitis B in special populations', Medical Journal of Viral Hepatitis, 4.2(2), pp. 63-68. doi: 10.21608/mjvh.2020.80654
Elsaid, E., Tarik, Z., Eman, M., Mostafa, E., Ahmed, A., Mohamed, A., Hoda, E. Management of chronic hepatitis B in special populations. Medical Journal of Viral Hepatitis, 2020; 4.2(2): 63-68. doi: 10.21608/mjvh.2020.80654

Management of chronic hepatitis B in special populations

Article 3, Volume 4.2, Issue 2, March 2020, Page 63-68  XML PDF (168.51 K)
Document Type: Review articles
DOI: 10.21608/mjvh.2020.80654
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Authors
Elbadrawy Elsaid1; Zaher Tarik1; Mousa Eman2; Elshenaway Mostafa3; Alhawarey Ahmed3; Abdel-Aziz Mohamed3; Elgamal Hoda3
1Tropical Medicine dept., Zagazig Univ., Zagazig, Egypt
2Faculty of Dentistry, Mansoura Univ., Egypt
3Tropical Medicine dept., Mansoura Univ, Mansoura, Egypt
Abstract
Hepatitis B infection is an international
healthcare problem, particularly in developing areas.
The hepatitis B virus (HBV) is frequently transmitted
via body fluids such as blood, semen, and vaginal
secretions. The majority of adults infected with the
virus recover, however 5%-10% are not capable to
clear the virus and become chronically infected. The
principal treatment goals for patients with hepatitis
B infection are to prevent progression of the liver
disease to cirrhosis or hepatocellular carcinoma. The
effective nucleos(t)ide analogs (NAs) against hepatitis
B virus (HBV) has improved the outcome of
patients with chronic hepatitis B (CHB). Special
populations infected with chronic HBV include
those with decompensated cirrhosis, organ transplantation,
pregnancy, extrahepatic manifestations,
immunosuppressive-chemotherapy, co-infections
(HIV-HCV- HDV), renal failure, hepatitis B virus
infection in children/adolescents and dental practice.
These populations vary in their natural history and
risk of liver-related complications, the indications
for anti-HBV treatment in addition to the recommendations
concerning the HBV drugs used, time
of therapy and expected endpoints. The aim of
this review is to summarize the information on the
relevance and treatment of HBV infection in such
special populations.
Keywords
Hepatitis B virus; Cirrhosis; Pregnancy; HBV-HCV coinfection; HBV Reactivation; Nucleos(t)ide analogues and dental practice
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