Amr, S., Ahmed, A., Hoda, E. (2018). Spontaneous Bacterial Peritonitis: An Overview. Medical Journal of Viral Hepatitis, 3.1(1), 13-17. doi: 10.21608/mjvh.2018.55751
Samir Amr; Abdel-Razik Ahmed; Elgamal Hoda. "Spontaneous Bacterial Peritonitis: An Overview". Medical Journal of Viral Hepatitis, 3.1, 1, 2018, 13-17. doi: 10.21608/mjvh.2018.55751
Amr, S., Ahmed, A., Hoda, E. (2018). 'Spontaneous Bacterial Peritonitis: An Overview', Medical Journal of Viral Hepatitis, 3.1(1), pp. 13-17. doi: 10.21608/mjvh.2018.55751
Amr, S., Ahmed, A., Hoda, E. Spontaneous Bacterial Peritonitis: An Overview. Medical Journal of Viral Hepatitis, 2018; 3.1(1): 13-17. doi: 10.21608/mjvh.2018.55751
Tropical Medicine dept, Faculty of Medicine, Mansoura Univ., Egypt
Abstract
Spontaneous bacterial peritonitis (SBP) is a risky complication that occurs amongst cirrhotic patients with ascites. SBP develops in approximately 10 to 30% and has an estimated inhospital mortality rate of 20%. SBP outcomes from translocation of bacteria from the intestinal lumen. Also, SBP results from a bacteremia that initiates at a distant site, such as a urinary tract infection. The majority of cases of SBP are produced by gram-negative enteric organisms, such as Escherichia coli and Klebsiella pneumonia. Third-generation, broad-spectrum cephalosporins continue a good initial choice for SBP treatment. Levofloxacin is an acceptable alternative for patients not receiving long-term flouroquinolone prophylaxis or for those with a penicillin allergy. Different antibiotics such as pipercillintazobactam should be considered for patients with nosocomial SBP or for patients who fail to improve on traditional antibiotic regimens.