Acute on chronic hepatic failure due to hepatitis B infection: A case report

Document Type : Original article

Authors

1 Department of Medicine, Ladoke Akintola University of Technology, Ogbomosho

2 Department of Medicine, Ladoke Akintola University of Technology, Ogbomosho, Oyo State, Nigeria.

3 Nigerian Navy Reference Hospital, Ojo, Nigeria.

4 Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomosho Oyo State, Nigeria.

Abstract

Background: Acute on chronic liver failure, also known as acutely decompensated cirrhosis, is a clinical condition characterized by sudden hepatic decompensation in patients with pre-existing chronic liver dysfunction, as well as extrahepatic organ defects and increase mortality in some patients.The prevalence of acute on chronic liver failure and the associated mortality rate is high in both developed and developing countries. We report the case of a 19 year old male patient with a three year history of hepatitis B virus infection who presented to the hospital with jaundice and progressive generalized body swelling. Six days later, the patient developed hematemesis, ascites, melena and progressive body weakness. We present a case report and a review of literature on acute on chronic hepatic failure with a focus on the role of chronic hepatitis B infection.

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