Adetunji, B., Alare, K., Afolabi, S., Olajire, A., Adegboye, O. (2021). Acute on chronic hepatic failure due to hepatitis B infection: A case report. Medical Journal of Viral Hepatitis, 5.3(3), 27-31. doi: 10.21608/mjvh.2021.193443
Busayo Adetunji; Kehinde Alare; Samson Afolabi; Akinbode Olajire; Oyaronbi Adegboye. "Acute on chronic hepatic failure due to hepatitis B infection: A case report". Medical Journal of Viral Hepatitis, 5.3, 3, 2021, 27-31. doi: 10.21608/mjvh.2021.193443
Adetunji, B., Alare, K., Afolabi, S., Olajire, A., Adegboye, O. (2021). 'Acute on chronic hepatic failure due to hepatitis B infection: A case report', Medical Journal of Viral Hepatitis, 5.3(3), pp. 27-31. doi: 10.21608/mjvh.2021.193443
Adetunji, B., Alare, K., Afolabi, S., Olajire, A., Adegboye, O. Acute on chronic hepatic failure due to hepatitis B infection: A case report. Medical Journal of Viral Hepatitis, 2021; 5.3(3): 27-31. doi: 10.21608/mjvh.2021.193443
Acute on chronic hepatic failure due to hepatitis B infection: A case report
1Department of Medicine, Ladoke Akintola University of Technology, Ogbomosho
2Department of Medicine, Ladoke Akintola University of Technology, Ogbomosho, Oyo State, Nigeria.
3Nigerian Navy Reference Hospital, Ojo, Nigeria.
4Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomosho Oyo State, Nigeria.
Abstract
Background: Acute on chronic liver failure, also known as acutely decompensated cirrhosis, is a clinical condition characterized by sudden hepatic decompensation in patients with pre-existing chronic liver dysfunction, as well as extrahepatic organ defects and increase mortality in some patients.The prevalence of acute on chronic liver failure and the associated mortality rate is high in both developed and developing countries. We report the case of a 19 year old male patient with a three year history of hepatitis B virus infection who presented to the hospital with jaundice and progressive generalized body swelling. Six days later, the patient developed hematemesis, ascites, melena and progressive body weakness. We present a case report and a review of literature on acute on chronic hepatic failure with a focus on the role of chronic hepatitis B infection.