Hepatopulmonary syndrome: A recent review of the literature

Document Type : Review articles

Authors

Tropical Medicine dept, Faculty of Medicine, Mansoura Univ., Egypt

Abstract

Hepatopulmonary syndrome (HPS) is a serious vascular
complication of liver disease reported to be present in 4-32%
of cirrhotic adults and 9-20% of children. HPS diagnosis
depends on the presence of a triad of liver disease with intrapulmonary
vascular dilation that causes abnormal arterial oxygenation.
Pulmonary microvascular dilation and angiogenesis
are two central mechanisms in pathogenesis of HPS. No effective
medical therapies are currently available and liver transplantation is
the only established treatment option.

Keywords