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Elhadidy, A., Elorbany, A., balah, E., Elghnam, A., Elghandou, N. (2023). Acute Epstein-Barr virus Encephalitis and hepatitis without mononucleosis syndrome: a case report. Medical Journal of Viral Hepatitis, 7.3(3), 15-17. doi: 10.21608/mjvh.2023.334428
Abdelmoneim Elhadidy; Abdelmoneim Elorbany; Emad balah; Ali Elghnam; Nereen Elghandou. "Acute Epstein-Barr virus Encephalitis and hepatitis without mononucleosis syndrome: a case report". Medical Journal of Viral Hepatitis, 7.3, 3, 2023, 15-17. doi: 10.21608/mjvh.2023.334428
Elhadidy, A., Elorbany, A., balah, E., Elghnam, A., Elghandou, N. (2023). 'Acute Epstein-Barr virus Encephalitis and hepatitis without mononucleosis syndrome: a case report', Medical Journal of Viral Hepatitis, 7.3(3), pp. 15-17. doi: 10.21608/mjvh.2023.334428
Elhadidy, A., Elorbany, A., balah, E., Elghnam, A., Elghandou, N. Acute Epstein-Barr virus Encephalitis and hepatitis without mononucleosis syndrome: a case report. Medical Journal of Viral Hepatitis, 2023; 7.3(3): 15-17. doi: 10.21608/mjvh.2023.334428

Acute Epstein-Barr virus Encephalitis and hepatitis without mononucleosis syndrome: a case report

Article 3, Volume 7.3, Issue 3, December 2023, Page 15-17  XML PDF (149.86 K)
Document Type: Original article
DOI: 10.21608/mjvh.2023.334428
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Authors
Abdelmoneim Elhadidy email 1; Abdelmoneim Elorbany2; Emad balah1; Ali Elghnam1; Nereen Elghandou3
1Gastroenterology and Hepatology department, Damietta Fever Hospital, Egypt.
2Gastroenterology and Hepatology department, Damietta Fever Hospital, Egypt
3Clinical pharmacy department, Damietta Fever Hospital, Egypt.
Abstract
Background: Epstein-Barr virus (EBV) mononucleosis is rarely associated with central nervous system (CNS) abnormalities, which usually appear later in the course of the illness. Neurological disorders caused by EBV infectious mononucleosis include optic neuritis, transverse myelitis, aseptic meningitis, encephalitis, meningoencephalitis, cranial nerve (CN) palsies, and Guillain-Barré syndrome. Primary EBV infection often leads to elevated liver enzymes and infectious mononucleosis syndrome, but acute symptomatic hepatitis without typical EBV presentations is relatively uncommon. We present the case of a 12-year-old male who presented with fever, lethargy, and unusual behavior for one day, and fever for five days. The physical examination results were normal. Changes in EBV specific antibodies and EBV-PCR were used to diagnose EBV encephalitis when normal examinations revealed symptoms of acute hepatitis.
Keywords
Encephalitis; hepatitis; Epstein-Barr virus
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