Nanoparticle zinc oxide obviates oxidative stress of liver cells in induced-diabetes mellitus model

Document Type : Original article

Authors

• Alaa Elmetwalli ¹
• Jihan Hassan ²
• Heba Alaa ³
• Mervat G. Hassan ³
• Mohamed Ali ⁴
• M. Fikry Eltayeb ³
• Eman Mousa ⁵
• Mohamed Salah ⁶
• Mohammed Abdelaziz ⁶
• Khaled Taha ⁷
• Ola El-Emam ⁸
• Sama A. EL-Sakka ⁹
• Amina M. Tolba ¹⁰
• Alaa Habib ⁷

¹ Department of Clinical Trial Research Unit and Drug Discovery, Egyptian Liver Research Institute and Hospital (ELRIAH), Mansoura, Egypt.

² Colleague Medical Research Institute, Department of Applied Medical Chemistry, Medical Research Institute, Alexandria University, Alexandria, Egypt.

³ Department of Botany and Microbiology, Faculty of Science, Benha University, Benha 33516, Egypt.

⁴ Biochemistry Division, Chemistry Department, Faculty of Science, Zagazig University 44519

⁵ Faculty of Dentistry, Mansoura University, Mansoura, Egypt.

⁶ Tropical Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

⁷ Internal Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

⁸ Clinical Pathology Department, Mansoura University, Mansoura, Egypt.

⁹ Animal Physiology, Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt

¹⁰ Department of Anatomy, Faculty of Medicine, for Girls, Al-Azhar University, Cairo, Egypt

Abstract

Keywords

• Nano zinc oxide
• oxidative stress, streptozotocin, hepatic disorders, and diabetes mellitus